Hitoshi SHINOTOH: search on Z-Library

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1

Positron emission tomographic measurement of acetylcholinesterase activity reveals differential loss of ascending cholinergic systems in Parkinson's disease and progressive supranuclear palsy

Hitoshi Shinotoh, Hiroki Namba, Mika Yamaguchi, Kiyoshi Fukushi, Shin-Ichiro Nagatsuka, Masaomi Iyo, Masto Asahina, Takamichi Hattori, Shuzi Tanada, Toshiaki Irie

Journal:

Annals of Neurology

Year:

1999

Language:

english

File:

PDF, 522 KB

english, 1999

2

Progressive loss of cortical acetylcholinesterase activity in association with cognitive decline in Alzheimer's disease: A positron emission tomography study

Hitoshi Shinotoh, Hiroki Namba, Kiyoshi Fukushi, Shin-Ichiro Nagatsuka, Noriko Tanaka, Akiyo Aotsuka, Tsuneyoshi Ota, Shuji Tanada, Toshiaki Irie

Journal:

Annals of Neurology

Year:

2000

Language:

english

File:

PDF, 394 KB

english, 2000

3

Parkinsonism induced by solvent abuse

Dr. Ryan J. Uitti, Barry J. Snow, Hitoshi Shinotoh, Francois J. G. Vingerhoets, Margo Hayward, Stanley Hashimoto, John Richmond, Sanford P. Markey, Carol J. Markey, Donald B. Calne

Journal:

Annals of Neurology

Year:

1994

Language:

english

File:

PDF, 481 KB

english, 1994

4

PET study of brain acetylcholinesterase in cerebellar degenerative disorders

Shigeki Hirano, Hitoshi Shinotoh, Kimihito Arai, Akiyo Aotsuka, Fumihiko Yasuno, Noriko Tanaka, Tsuneyoshi Ota, Koichi Sato, Kiyoshi Fukushi, Shuji Tanada, Takamichi Hattori, Toshiaki Irie

Journal:

Movement Disorders

Year:

2008

Language:

english

File:

PDF, 156 KB

english, 2008

5

Detection of benzodiazepine receptor occupancy in the human brain by positron emission tomography

Hitoshi Shinotoh, Masaomi Iyo, Tatsuo Yamada, Osamu Inoue, Kazutoshi Suzuki, Takashi Itoh, Hiroshi Fukuda, Toshiro Yamasaki, Yukio Tateno, Keizo Hirayama

Journal:

Psychopharmacology

Year:

1989

Language:

english

File:

PDF, 637 KB

english, 1989

6

A simple method for the detection of abnormal brain regions in Alzheimer’s disease patients using [11C]MP4A: Comparison with [123I]IMP SPECT

Tsuneyoshi Ota, Hitoshi Shinotoh, Kiyoshi Fukushi, Shin-ichiro Nagatsuka, Hiroki Namba, Masaomi Iyo, Akiyo Aotsuka, Noriko Tanaka, Koichi Sato, Tetsuya Shiraishi, Shuji Tanada, Heii Arai, Toshiaki Iri

Journal:

Annals of Nuclear Medicine

Year:

2004

Language:

english

File:

PDF, 2.25 MB

english, 2004

7

Relationship between striatal [123I]β-CIT binding and four major clinical signs in Parkinson’s disease

Hitoshi Shinotoh, Yoshitaka Uchida, Hisao Ito, Takamichi Hattori

Journal:

Annals of Nuclear Medicine

Year:

2000

Language:

english

File:

PDF, 460 KB

english, 2000

8

Human cerebral acetylcholinesterase activity measured with positron emission tomography: procedure, normal values and effect of age

Hiroki Namba, Masaomi Iyo, Kiyoshi Fukushi, Hitoshi Shinotoh, Shin-ichiro Nagatsuka, Tetsuya Suhara, Yasuhiko Sudo, Kazutoshi Suzuki, Toshiaki Irie

Journal:

European Journal of Nuclear Medicine and Molecular Imaging

Year:

1999

Language:

english

File:

PDF, 158 KB

english, 1999

9

Neuroimaging of PD, PSP, CBD and MSA—PET and SPECT studies

Hitoshi Shinotoh

Journal:

Journal of Neurology

Year:

2006

Language:

english

File:

PDF, 310 KB

english, 2006

10

Beyond PIB: the next generation of amyloid-imaging ligands

Hitoshi SHINOTOH, Tetsuya SUHARA

Journal:

Psychogeriatrics

Year:

2008

Language:

english

File:

PDF, 52 KB

english, 2008

11

Positron Emission Tomographic Measurement of Brain Acetylcholinesterase Activity Using N-[11C]methylpiperidin-4-yl Acetate Without Arterial Blood Sampling: Methodology of Shape Analysis and its Diagnostic Power for Alzheimer's Disease

Tanaka, Noriko, Fukushi, Kiyoshi, Shinotoh, Hitoshi, Nagatsuka, Shin-ichiro, Namba, Hiroki, Iyo, Masaomi, Aotsuka, Akiyo, Ota, Tsuneyoshi, Tanada, Shuji, Irie, Toshiaki

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2001

Language:

english

File:

PDF, 3.26 MB

english, 2001

12

Kinetic Analysis of [ 11 C]MP4A Using a High-Radioactivity Brain Region That Represents an Integrated Input Function for Measurement of Cerebral Acetylcholinesterase Activity Without Arterial Blood Sampling

Nagatsuka, Shin-ichiro, Fukushi, Kiyoshi, Shinotoh, Hitoshi, Namba, Hiroki, Iyo, Masaomi, Tanaka, Noriko, Aotsuka, Akiyo, Ota, Tsuneyoshi, Tanada, Shuji, Irie, Toshiaki

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2001

Language:

english

File:

PDF, 4.08 MB

english, 2001

13

Evaluation of Simplified Kinetic Analyses for Measurement of Brain Acetylcholinesterase Activity Using N-[11C]Methylpiperidin-4-yl Propionate and Positron Emission Tomography

Sato, Koichi, Fukushi, Kiyoshi, Shinotoh, Hitoshi, Nagatsuka, Shinichiro, Tanaka, Noriko, Aotsuka, Akiyo, Ota, Tsuneyoshi, Shiraishi, Tetsuya, Tanada, Shuji, Iyo, Masaomi, Irie, Toshiaki

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2004

Language:

english

File:

PDF, 687 KB

english, 2004

14

Molecular imaging of dementia

Takaaki MORI, Jun MAEDA, Hitoshi SHIMADA, Makoto HIGUCHI, Hitoshi SHINOTOH, Shu-ichi UENO, Tetsuya SUHARA

Journal:

Psychogeriatrics

Year:

2012

Language:

english

File:

PDF, 1.77 MB

english, 2012

15

The presymptomatic period in a patient with idiopathic parkinsonism

Hitoshi Shinotoh, Francois J.G. Vingerhoets, Michael Schulzer, Barry J. Snow

Journal:

Parkinsonism & Related Disorders

Year:

1996

Language:

english

File:

PDF, 445 KB

english, 1996

16

Cortical amyloid deposition in Lewy body diseases with dementia demonstrated by PET

Hitoshi Shimada, Hitoshi Shinotoh, Michie Miyoshi, Shigeki Hirano, Koichi Sato, Noriko Tanaka, Tsuneyoshi Ota, Kiyoshi Fukushi, Toshiaki Irie, Hiroshi Ito, Tetsuya Suhara

Journal:

Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 101 KB

english, 2009

17

Mapping of brain acetylcholinesterase alterations in Lewy body disease by PET

Hitoshi Shimada, Shigeki Hirano, Hitoshi Shinotoh, Akiyo Aotsuka, Kouichi Sato, Noriko Tanaka, Tsuneyoshi Ota, Masato Asahina, Kiyoshi Fukushi, Toshiaki Irie, Tetsuya Suhara

Journal:

Neuroscience Research

Year:

2010

Language:

english

File:

PDF, 80 KB

english, 2010

18

Dementia with Lewy bodies can be well-differentiated from Alzheimer's disease by measurement of brain acetylcholinesterase activity by PET

Hitoshi Shimada, Shigeki Hirano, Hitoshi Shinotoh, Koichi Sato, Noriko Tanaka, Tsuneyoshi Ota, Masato Asahina, Akiyo Aotsuka, Hiroshi Ito, Kiyoshi Fukushi, Satoshi Kuwabara, Toshiaki Irie, Tetsuya Suh

Journal:

Neuroscience Research

Year:

2011

Language:

english

File:

PDF, 114 KB

english, 2011

19

In vivo detection of neuropathologic changes in presymptomatic MAPT mutation carriers: A PET and MRI study

Michie Miyoshi, Hitoshi Shinotoh, Zbigniew K. Wszolek, Audrey J. Strongosky, Hitoshi Shimada, Ryosuke Arakawa, Makoto Higuchi, Yoko Ikoma, Fumihiko Yasuno, Kiyoshi Fukushi, Toshiaki Irie, Hiroshi Ito,

Journal:

Parkinsonism & Related Disorders

Year:

2010

Language:

english

File:

PDF, 306 KB

english, 2010

20

Preserved acetylcholinesterase activity in aged cerebral cortex

Hiroki Namba, Masaomi lyo, Hitoshi Shinotoh, Sin-ichiro Nagatsuka, Kiyoshi Fukushi, Toshiaki Irie

Journal:

Year:

1998

Language:

english

File:

PDF, 189 KB

english, 1998

21

Positron emission tomography: quantitative measurement of brain acetylcholinesterase activity using radiolabeled substrates

Hiroki Namba, Kiyoshi Fukushi, Shin-ichiro Nagatsuka, Masaomi Iyo, Hitoshi Shinotoh, Shuji Tanada, Toshiaki Irie

Journal:

Year:

2002

Language:

english

File:

PDF, 283 KB

english, 2002

22

Biopterin metabolism in patients with malignant syndrome

Hiroshi Ichinose, Tamae Ohye, Hitoshi Shinotoh, Kimihito Arai, Shunzo Yamazaki, Eiji Mizuta, Sadako Kuno, Toshiharu Nagatsu

Journal:

Parkinsonism & Related Disorders

Year:

2003

Language:

english

File:

PDF, 142 KB

english, 2003

23

Questionnaire-based assessment of pelvic organ dysfunction in Parkinson's disease

Ryuji Sakakibara, Hitoshi Shinotoh, Tomoyuki Uchiyama, Mitsufumi Sakuma, Masahide Kashiwado, Mitsuharu Yoshiyama, Takamichi Hattori

Journal:

Autonomic Neuroscience

Year:

2001

Language:

english

File:

PDF, 640 KB

english, 2001

24

P1-143: Cholinergic system is impaired in the early stage of Parkinson’s disease -in vivo brain acetylcholinesterase measurement by PET

Shigeki Hirano, Hitoshi Shinotoh, Masato Asahina, Koichi Sato, Tsuneyoshi Ota, Noriko Tanaka, Kiyoshi Fukushi, Shuji Tanada, Takamichi Hattori, Toshiaki Irie

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 129 KB

english, 2006

25

P-059: Voxel-based analysis of [11C]PIB uptake in Alzheimer’s disease and mild cognitive impairment

Hitoshi Shinotoh, Fukushi Kiyoshi, Shigeki Hirano, Hitoshi Shimada, Noriko Tanaka, Tsuneyoshi Ota, Koichi Sato, Tetsuya Suhara, Toshiaki Irie

Journal:

Alzheimer's & Dementia

Year:

2007

Language:

english

File:

PDF, 51 KB

english, 2007

26

IC-01-05: Mapping of amyloid deposition in early- and late-onset Alzheimer's disease

Hitoshi Shinotoh

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 220 KB

english, 2008

27

P1-266: Changes in beta-amyloid deposition by pet study

Michie Miyoshi, Hitoshi Shinotoh, Hitoshi Shimada, Kouichi Sato, Kiyoshi Fukushi, Hiroshi Ito, Tetsuya Suhara, Masayasu Matsumoto, Toshiaki Irie

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 111 KB

english, 2008

28

Lewy body disease with dementia can be well-differentiated from Alzheimer's disease by measurement of cerebral cortical acetylcholinesterase activity by PET

Hitoshi Shimada, Hitoshi Shinotoh, Shigeki Hirano, Michie Miyoshi, Koichi Sato, Noriko Tanaka, Tsuneyoshi Ota, Masato Asahina, Akiyo Aotsuka, Kiyoshi Fukushi, Hiroshi Ito, Satoshi Kuwabara, Toshiaki I

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 50 KB

english, 2010

29

Longitudinal [11C]PIB PET study in healthy elderly persons, patients with mild cognitive impairment, and Alzheimer's disease

Hitoshi Shinotoh, Hitoshi Shimada, Shigeki Hirano, Noriko Tanaka, Koichi Sato, Fukushi Kiyoshi, Irie Toshiaki, Yoko Eguchi, Hiroshi Ito, Tetsuya Suhara

Journal:

Alzheimer's & Dementia

Year:

2011

Language:

english

File:

PDF, 82 KB

english, 2011

30

In vivo detection of amyloid deposition using [11C]AZD2184 PET

Hitoshi Shimada, Hitoshi Shinotoh, Shigeki Hirano, Takaaki Mori, Yoko Eguchi, Noriko Tanaka, Fumitoshi Kodaka, Hironobu Fujiwara, Yasuyuki Kimura, Satoshi Kuwabara, Harumasa Takano, Makoto Higuchi, Hi

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 164 KB

english, 2012

31

In vivo detection of amyloid deposition using [11C]AZD2184 PET

Hitoshi Shimada, Hitoshi Shinotoh, Shigeki Hirano, Takaaki Mori, Yoko Eguchi, Noriko Tanaka, Fumitoshi Kodaka, Hironobu Fujiwara, Yasuyuki Kimura, Satoshi Kuwabara, Harumasa Takano, Makoto Higuchi, Hi

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 162 KB

english, 2012

32

Measurement of acetylcholinesterase by positron emission tomography in the brains of healthy controls and patients with Alzheimer's disease

Masaomi Iyo, Hiroki Namba, Kiyoshi Fukushi, Hitoshi Shinotoh, Shinichiro Nagatsuka, Tetsuya Suhara, Yasuhiko Sudo, Kazutoshi Suzuki, Toshiaki Irie

Journal:

Year:

1997

Language:

english

File:

PDF, 95 KB

english, 1997

33

Quantitative in vivo analysis of benzodiazepine binding sites in the human brain using positron emission tomography

Masaomi Iyo, Takashi Itoh, Toshiro Yamasaki, Hiroshi Fukuda, Osamu Inoue, Hitoshi Shinotoh, Kazutoshi Suzuki, Susumu Fukui, Yukio Tateno

Journal:

Neuropharmacology

Year:

1991

Language:

english

File:

PDF, 872 KB

english, 1991

34

A short-scan method for k3 estimation with moderately reversible PET ligands: Application of irreversible model to early-phase PET data

Koichi Sato, Kiyoshi Fukushi, Hitoshi Shinotoh, Hitoshi Shimada, Noriko Tanaka, Shigeki Hirano, Toshiaki Irie

Journal:

Year:

2012

Language:

english

File:

PDF, 855 KB

english, 2012

35

SPECT imaging of the dopamine transporter with [123I]-β-CIT reveals marked decline of nigrostriatal dopaminergic function in Parkinson's disease with urinary dysfunction

Ryuji Sakakibara, Hitoshi Shinotoh, Tomoyuki Uchiyama, Mitsuharu Yoshiyama, Takamichi Hattori, Tomonori Yamanishi

Journal:

Journal of the Neurological Sciences

Year:

2001

Language:

english

File:

PDF, 94 KB

english, 2001

36

Intracranial dural arteriovenous fistula (DAVF) presenting progressive dementia and parkinsonism

Shinji Matsuda, Masaaki Waragai, Hitoshi Shinotoh, Nobuyoshi Takahashi, Kenji Takagi, Takamichi Hattori

Journal:

Journal of the Neurological Sciences

Year:

1999

Language:

english

File:

PDF, 448 KB

english, 1999

37

MRI based ROI evaluation of MP4A-PET images

Noriko Tanaka, Hajime Matsuura, Toshiaki Irie, Kiyoshi Fukushi, Shin-ichiro Nagatsuka, Hitoshi Shinotoh, Akiyo Aotsuka, Tsuneyoshi Oota

Journal:

Year:

2001

Language:

english

File:

PDF, 81 KB

english, 2001

38

Imaging of Tau Pathology in a Tauopathy Mouse Model and in Alzheimer Patients Compared to Normal Controls

Maruyama, Masahiro, Shimada, Hitoshi, Suhara, Tetsuya, Shinotoh, Hitoshi, Ji, Bin, Maeda, Jun, Zhang, Ming-Rong, Trojanowski, John Q., Lee, Virginia M.-Y., Ono, Maiko, Masamoto, Kazuto, Takano, Haruma

Journal:

Year:

2013

Language:

english

File:

PDF, 5.80 MB

english, 2013

39

Noninvasive k3estimation method for slow dissociation PET ligands: application to [11C]Pittsburgh compound B

Sato, Koichi, Fukushi, Kiyoshi, Shinotoh, Hitoshi, Shimada, Hitoshi, Hirano, Shigeki, Tanaka, Noriko, Suhara, Tetsuya, Irie, Toshiaki, Ito, Hiroshi

Journal:

EJNMMI Research

Year:

2013

Language:

english

File:

PDF, 416 KB

english, 2013

40

P2-276

Shinotoh, Hitoshi, Fukushi, Kiyoshi, Tanaka, Noriko, Ota, Tsuneyoshi, Hirano, Shigeki, Sato, Koichi, Shimada, Hitoshi, Tanada, Shuji, Irie, Toshiaki

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 110 KB

english, 2006

41

P2-080: Mapping of amyloid deposition in early- and late-onset Alzheimer's disease

Shinotoh, Hitoshi

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 368 KB

english, 2008

42

Whose body is it anyway? 3: Leave your body behind

Shimada, Hitoshi, Higuchi, Makoto, Ikoma, Yoko, Shinotoh, Hitoshi, Furukawa, Shogo, Moriguchi, Sho, Eguchi, Yogo, Nogami, Tsuyoshi, Nagashima, Tomohisa, Suzuki, Masayuki, Takahata, Keisuke, Sasaki, Ke

Journal:

Year:

2009

Language:

english

File:

PDF, 82 KB

english, 2009

43

In vivo visualization of tau pathology

Shimada, Hitoshi, Higuchi, Makoto, Ikoma, Yoko, Shinotoh, Hitoshi, Furukawa, Shogo, Moriguchi, Sho, Eguchi, Yogo, Nogami, Tsuyoshi, Nagashima, Tomohisa, Suzuki, Masayuki, Takahata, Keisuke, Sasaki, Ke

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 528 KB

english, 2013

44

Age correlates with cortical acetylcholinesterase decline in Alzheimer's disease patients: A PET study

Hirano, Shigeki, Shinotoh, Hitoshi, Shimada, Hitoshi, Tanaka, Noriko, Ota, Tsuneyoshi, Sato, Koichi, Kuwabara, Satoshi, Toshiaki, Irie, Suhara, Tetsuya

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 270 KB

english, 2012

45

IC-104-03

Shinotoh, Hitoshi, Fukushi, Kiyoshi, Tanaka, Noriko, Ota, Tsuneyoshi, Hirano, Shigeki, Sato, Koichi, Shimada, Hitoshi, Tanada, Shuji, Irie, Toshiaki

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 57 KB

english, 2006

46

Age correlates with cortical acetylcholinesterase decline in Alzheimer's disease patients: A PET study

Hirano, Shigeki, Shinotoh, Hitoshi, Shimada, Hitoshi, Tanaka, Noriko, Ota, Tsuneyoshi, Sato, Koichi, Kuwabara, Satoshi, Toshiaki, Irie, Suhara, Tetsuya

Journal:

Alzheimer's & Dementia

Year:

2012

Language:

english

File:

PDF, 206 KB

english, 2012

47

IC-P-014

Tanaka, Noriko, Shinotoh, Hitoshi, Fukushi, Kiyoshi, Ota, Tsuneyoshi, Hirano, Shigeki, Sato, Koichi, Shimada, Hitoshi, Tanada, Shuji, Irie, Toshiaki

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 145 KB

english, 2006

48

In vivo visualization of tau pathology in Alzheimer's disease patients by [11C]PBB3-PET

Shimada, Hitoshi, Higuchi, Makoto, Shinotoh, Hitoshi, Hirano, Shigeki, Eguchi, Yoko, Kimura, Yasuyuki, Yamada, Makiko, Maruyama, Masahiro, Takano, Harumasa, Ito, Hiroshi, Suhara, Tetsuya

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 51 KB

english, 2013

49

Correlation between cerebral blood flow and amyloid deposition in Alzheimer's disease studied by [11C]PIB PET

Shinotoh, Hitoshi, Shimada, Hioshi, Miyoshi, Miche, Hirano, Shigeki, Tanaka, Noriko, Sato, Koichi, Fukushi, Kiyoshi, Irie, Toshiaki, Ito, Hiroshi, Suhara, Tetsuya

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 158 KB

english, 2010

50

Lewy Body Disease With Dementia can be Well-Differentiated from Alzheimer's Disease By Measurement of Cerebral Cortical Acetylcholinesterase Activity by PET

Shimada, Hitoshi, Shinotoh, Hitoshi, Hirano, Shigeki, Miyoshi, Michie, Sato, Koichi, Tanaka, Noriko, Ota, Tsuneyoshi, Asahina, Masato, Aotsuka, Akiyo, Fukushi, Kiyoshi, Ito, Hiroshi, Kuwabara, Satoshi

Journal:

Alzheimer's & Dementia

Year:

2010

Language:

english

File:

PDF, 66 KB

english, 2010

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